Department of Animal Molecular Biology

Conducts research, research and development, implementation, dissemination works and trainings in the field of:

  • use of microsatellite DNA sequence polymorphism to characterize the genetic structure of various breeds of farm animals and to assess population genetic variability,
  • identification of polymorphisms in genes conditioning resistance (susceptibility) to disease and associated with the occurrence of malformations in farm animals,
  • identification of immunoglobulin markers of farm animals with the aim of establishing correlations with health,
  • analysis of specialized chromosome structures in the karyotype of farm animals as part of the assessment of the phenomena of polymorphism and genetic conservatism,
  • comparative research of the genomes of various animals in the context of evolutionary changes,
  • evaluation of the genome of farm animals in the context of the effect of mutagenic factors and aging processes,
  • improvement of cytogenetic and molecular methods used in genome evaluation,
  • genome scanning in search of SNP markers of production traits and monitoring of biodiversity of farm animals,
  • study of epigenetic mechanisms of gene expression regulation (DNA methylation),
  • evaluation of genome organization within chromosomes and the influence of higher DNA organizational structures on gene expression,
  • identification of CNV (copy number variation) areas and linkage disequilibrium (LD) regions in the genomes of farm animals,
  • search for the basis of genetic diseases of farm animals based on highly efficient genomics techniques,
  • proteomic identification of biomarkers characteristic for productive traits of breeding animals, disease conditions and genetic defects and also giving the possibility of evaluating the influence of environment on immune system,
  • study of proteome of raw materials originating from breeding animals,
  • the development of the base of proteomic characteristics of raw materials and food products of animal origin.

Conducts the tasks in the field of:

  • pedigree verification of the following species of farm animals: cattle, sheep, goats, pigs and horses with regard to type I and II genetic markers,
  • monitoring of the population of farm animals for genetic defects, DNA mutations and genetic resistance and susceptibility determinants,
  • identification of the components of animal origin in feed mixtures with the application of the analysis of chosen regions of mitochondrial DNA,
  • establishing SNP genotypes based on microarrays as part of the programme of genomic selection of dairy cattle.

The Laboratory of Genomics, the Laboratory of Molecular Genetics, the Laboratory of Proteomics and the Laboratory of Cytogenetics function within the Department.